SHUNYI ZHAO · JIANGNAN UNIVERSITY

Automation and Intelligent Systems
for Biochemical Processes

Jiangnan University · Wuxi, China

Shunyi Zhao Research Group

Estimation · Control · Automation

Research overview

Research focus

Our research focuses on automation and intelligent systems for biochemical processes.

Our research connects process sensing, knowledge-guided modeling, intelligent control and autonomous experimentation. We investigate how measurements, biochemical process knowledge and learning can support reliable decisions under changing conditions, uncertainty and practical experimental constraints.

Illustrated biochemical process feedback loop. Measurements support models and estimation. Online estimates guide current control, while assessed experimental results guide subsequent experimental design.
Figure 01
Feedback control and experimental design for biochemical processes.Online estimates guide current feedback control. Assessed experimental results guide the design of subsequent experiments.

Research themes

Sensing and State Estimation

Soft sensing and inference of biochemical process states from online signals and laboratory measurements, accounting for uncertainty, sparse sampling and delayed results.

Process Modeling and Learning

Combining biochemical mechanisms, process data and transferable knowledge to learn dynamic models, guided by physical constraints and changing operating conditions.

Intelligent Control and Optimization

Feedback and predictive control of biochemical processes, with disturbance rejection and optimization of operating conditions under process, quality and resource constraints.

Autonomous Experimentation

Selecting experimental conditions and measurements, coordinating instruments and execution, and using returned results to guide subsequent biochemical experiments.

Selected publications

State estimation & filtering
  1. 2026

    State Estimation With Model Uncertainty Using Structure Variational Bayesian and Transfer Learning

    Shuang Gao, Xiaoli Luan, Biao Huang, Shunyi Zhao and Fei Liu · IEEE/CAA Journal of Automatica Sinica, 13(3), 715–727.

  2. 2024

    Fast Bayesian filtering for wastewater treatment plants with inaccurate process noise statistics

    Ke Li, Xiaojie Li, Xunyuan Yin, Shunyi Zhao, Biao Huang and Fei Liu · Computers & Chemical Engineering, 189, 108811.

  3. 2023

    Tuning-Free Bayesian Estimation Algorithms for Faulty Sensor Signals in State-Space

    Shunyi Zhao, Ke Li, Choon Ki Ahn, Biao Huang and Fei Liu · IEEE Transactions on Industrial Electronics, 70(1), 921–929.

  4. 2020

    Trial-and-error or avoiding a guess? Initialization of the Kalman filter

    Shunyi Zhao and Biao Huang · Automatica, 121, 109184.

  5. 2017

    Bayesian state estimation on finite horizons: The case of linear state–space model

    Shunyi Zhao, Biao Huang and Yuriy S. Shmaliy · Automatica, 85, 91–99.

  6. 2017

    Iterative Residual Generator for Fault Detection With Linear Time-Invariant State–Space Models

    Shunyi Zhao and Biao Huang · IEEE Transactions on Automatic Control, 62(10), 5422–5428.

  7. 2017

    Linear Optimal Unbiased Filter for Time-Variant Systems Without Apriori Information on Initial Conditions

    Shunyi Zhao, Biao Huang and Fei Liu · IEEE Transactions on Automatic Control, 62(2), 882–887.

  8. 2015

    Minimum variance unbiased FIR filter for discrete time-variant systems

    Shunyi Zhao, Yuriy S. Shmaliy, Biao Huang and Fei Liu · Automatica, 53, 355–361.

Research projects

Research support

Professor Zhao’s research has received support from national and provincial programs, including:

  • National Natural Science Foundation of China: General and Young Scientists programs
  • Jiangsu Provincial Natural Science Foundation: Distinguished Young Scholars program

People

Faculty & students

Principal investigator

Shunyi Zhao

Professor · Doctoral Supervisor · Vice Dean

Shunyi Zhao is a Professor and doctoral supervisor at Jiangnan University. He serves as Vice Dean of the School of Automation and Intelligent Science (School of Internet of Things), with responsibility for research and international exchange.

His group pursues automation and intelligent systems for biochemical processes, connecting sensing and estimation, process modeling and learning, control and optimization, and autonomous experimentation.

Faculty members

Yang Sun孙阳

Assistant Professor

Yang Sun studies robust model predictive control, disturbance estimation and rejection, and optimal control for uncertain systems.

Ph.D. in Computer Application Technology, Jinan University, 2024.

yangsun@jiangnan.edu.cn

Tianyu Zhang张田雨

Assistant Professor

Tianyu Zhang studies Bayesian state estimation and transfer learning for dynamic systems with model uncertainty, unknown noise statistics and asynchronous measurements. Her research focuses on adaptive transfer, estimation stability and suppression of negative transfer.

Doctoral research in Control Science and Engineering, Jiangnan University.

tianyuzhang@jiangnan.edu.cn

Graduate students

Songyao Mu慕松垚

Target-state completion and pose recovery for embodied manipulation under occlusion.

Yuchen Tang汤宇辰

Xu Xu许栩

Zheng Zhou周政

Stochastic variational inference for state estimation in linear nonconjugate systems.

Contact

Academic collaboration and graduate research enquiries.

Institution
Jiangnan University
School
School of Automation and Intelligent Science
(School of Internet of Things)
Research unit
Key Laboratory of Advanced Process Control for Light Industry,
Ministry of Education
Email
shunyi@jiangnan.edu.cn
Address
1800 Lihu Avenue, Wuxi 214122, Jiangsu, China